BonesLabs Blog
Updates on our supply, methodology references, and notes from the bench — written by the BonesLabs team for the research community.
Showing 91-95 of 95 posts | page 6/6
ARA-290 (Cibinetide): A Non-Erythropoietic EPO-Derived Tissue-Protective Peptide Research summary. ARA-290, also known as cibinetide, is an 11-amino-acid peptide derived from the aqueous-exposed face of helix B of erythropoietin (EPO). It was engineered to retain the cytoprotective and anti-inflammatory properties of EPO while losing its haematopoietic (red-blood-cell-stimulating) activity. The peptide acts at the innate repair receptor […]
AOD9604: A Modified hGH Fragment Studied for Lipolytic Activity Research summary. AOD9604 is a synthetic hexadecapeptide derived from the C-terminal lipolytic domain of human growth hormone (hGH), specifically residues 177–191, with an added N-terminal tyrosine to improve stability. It was originally developed as an anti-obesity candidate by Metabolic Pharmaceuticals in Australia. The molecule retains hGH's […]
AICAR: An AMPK Activator at the Intersection of Metabolism and Inflammation Research summary. AICAR (5-aminoimidazole-4-carboxamide ribonucleoside) is a small-molecule purine nucleoside analogue rather than a true peptide. It is taken up by cells through adenosine transporters, phosphorylated intracellularly to ZMP (the 5'-monophosphate form), and acts as a direct allosteric activator of AMP-activated protein kinase (AMPK). […]
Adipotide (FTPP): A Vasculature-Targeted Proapoptotic Peptide Research summary. Adipotide — also referred to as FTPP (Fat-Targeted Proapoptotic Peptide) — is a synthetic chimeric peptidomimetic engineered to selectively trigger apoptosis in the vasculature supporting white adipose tissue. Rather than acting on adipocytes themselves, the molecule disrupts the capillary network that perfuses fat depots, leading to reductions […]
BPC-157: A Pentadecapeptide Studied in Tissue Repair and Cytoprotection Research summary. BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide derived from a stable fragment of a larger protein originally isolated from human gastric juice. The Sikiric laboratory in Zagreb, Croatia, has produced the most extensive body of preclinical work on the molecule over […]